Clydine is a female name with an American English pronunciation of KLY-deen (/klaɪˈdiːn/). It is a variation of the name Clyde. Clydine originated in the United States and has been recorded as far back as the early 20th century. While not currently ranked among the most popular names, it had moderate usage during the mid-20th century, peaking in the 1940s and 1950s. Clydine carries a sense of uniqueness and individuality, making it a distinctive choice for parents seeking a less common name for their baby girl.