Mylisa is a female name with American English pronunciation, pronounced as my-LY-suh (/maɪˈlaɪsə/). It is also sometimes spelled as Mylissa. The name Mylisa has been given to newborn girls in the United States since at least the 1960s. While it has not reached high levels of popularity, it has consistently appeared on the baby name charts over the years. Mylisa's origin is uncertain, but it is believed to be a variation of Melissa, which is of Greek origin and means "honey bee". The name Melissa has positive associations with sweetness and industry, making it a charming choice for parents looking for a unique yet meaningful name for their baby girl.